very interesting
http://rpgjs.com/
source code is available. You still need to have some scripting knowledge.
The big advantage is obviously deplyoment- the game will run on any platform.
There is an online gui frontend that is using it
http://rpgcreator.net/
disadvantage is no way to use it offline. You have to sign up with their servers with an account.
I wish the open source community focused their effort into making a frontend to rpgjs instead of reverse engineering enterbrain’s rpg makers.