Yes. GDevelop has two limitations that are shared with all game engines, and specifically any other game engines that utilize HTML5. The first would be the browser-based limit. Browsers have a hard limit of around 2000x2000 pixels for a single image (anything larger is scaled within memory so only the currently visible part is rendered, the rest is compressed in some cases), so that is the maximum supported by GDevelop since exported games are either run directly in a browser (web export) or wrapped in electron (which is a browser).
Older mobile devices will have even harsher limits, usually around 1000x1000 maximum for a single graphic resource.
The other limit would be GPUs.GPUs themselves actually have hard limits unless you’re doing on-the-fly texture compression, but that is usually only supported by brand new engines like Unreal 5. I include some of the math in another thread:
Overall, PixiJS (the renderer) runs in a browsers, and while it can technically support a size of 4096x4096, browsers do not. You’ll want to keep all of your assets under 2000x2000 max.